What do you do when your preparation for a procedure results in an incidental finding potentially of cancer? Congratulations to one of our partners on our publication regarding transcatheter aortic valve replacement (TAVR) and cancer attempting to inform this ethical discussion with empirical data in a particular case. (Link: https://pubmed.ncbi.nlm.nih.gov/32798041/). AI is rapidly transforming through Big Data health systems’ capacities globally to inform the pre-test probability or likelihood that an individual patient will benefit from a procedure to justify its clinical and financial costs. Do we not owe it to patients to ensure that this becomes as much as possible integral to the informed consent process, as part of a larger population health push for health equities getting the right care to the right patient at the right time?